Figure 4.
Association between immune reconstitution and GVHD in pediatric patients with NMD following URD HCT with Aba GVHD prophylaxis. Patients with aGVHD (patient IDs 1, 8, and 9) had an early dominance of CD4 T cells within lymphocytes (data not shown). Patients with any GVHD had higher percentage of proliferating (Ki67) or cytotoxic (Granzyme B) T cells. Those with cGVHD (patient IDs 1, 8, 9, and 10) had higher total number (data not shown) and percentage of B cells.

Association between immune reconstitution and GVHD in pediatric patients with NMD following URD HCT with Aba GVHD prophylaxis. Patients with aGVHD (patient IDs 1, 8, and 9) had an early dominance of CD4 T cells within lymphocytes (data not shown). Patients with any GVHD had higher percentage of proliferating (Ki67) or cytotoxic (Granzyme B) T cells. Those with cGVHD (patient IDs 1, 8, 9, and 10) had higher total number (data not shown) and percentage of B cells.

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