Kaplan-Meier estimated probabilities of EFS at 5 years. (A) The estimated EFS for the entire cohort was 65% (95% CI, 60% to 71%) at 1 year and 62% (56% to 57%) at 5 years post-HSCT. EFS at both 1 and 5 years post-HSCT were influenced by (B) IEI subgroup, (C) the presence of bronchiectasis at HSCT, (D) splenectomy prior to HSCT, and (E) the presence of hepatic dysfunction at HSCT. EFS at both 1 and 5 years post-HSCT were not influenced by (F) number of IEI-associated risk factors (bronchiectasis, colitis, malignancy, GLILD, hepatic comorbidity, and splenectomy), (G) HCT-CI score, (H) year of transplant, or (I) age at HSCT. Estimated EFS at 5 years (95% CI) are shown.