Kaplan-Meier estimates for CRNMB and MB during anticoagulant therapy. The 36-month cumulative incidence of CRNMB was 27.6% (95% CI, 23.1% to 32.8%). The 36-month cumulative incidence of MB was 16.0% (95% CI, 12.8% to 19.9%). The dashed lines indicate the upper and lower boundary of the 95% CI.