GARP-mediated activation of TGF-β1 by Tregs induces NK cell dysfunction after allo-HCT, which results in disease relapse. LAP, latency associated peptide, which prevents the binding of TGF-β1 to its receptor; OXPHOS, oxidative phosphorylation; mTOR, mammalian target of rapamycin. Professional illustration by Somersault18:24.