One- and two-way sensitivity analyses. (A) One-way sensitivity analysis of the cost of pola-R-CHP. In this analysis, we vary the cost of pola-R-CHP while keeping other parameters constant and show that pola-R-CHP is cost-effective if it costs less than $276 312 (blue dotted lines) at a WTP of $150 000. (B) Two-way sensitivity analysis of the 5-year PFS of pola-R-CHP and 5-year PFS of R-CHOP. In this analysis, we vary the 5-year PFS of pola-R-CHP and the 5-year PFS of R-CHOP simultaneously while keeping other parameters constant. The area shaded red represents the scenarios in which pola-R-CHP is the cost-effective strategy at a WTP of $150 000; the area shaded blue represents the scenarios in which pola-R-CHP is no longer the cost-effective strategy.