Graphs of cumulative QALYs gained and life-years gained. (A) Graph of cumulative QALYs gained over a lifetime horizon in pola-R-CHP compared with R-CHOP. The red curve represents the base case scenario in which R-CHOP and pola-R-CHP have similar rates of progression between 2 and 5 years, and additional QALYs are gained throughout the cohort’s lifetime. The green curve represents the optimistic scenario in which pola-R-CHP has a 75.1% 5-year PFS, and the blue curve represents the pessimistic scenario in which pola-R-CHP has a 5-year PFS of 62.6%. (B) Graph of cumulative life-years gained over a lifetime horizon in pola-R-CHP compared with R-CHOP. The red curve represents the base case scenario in which R-CHOP and pola-R-CHP have similar rates of progression between 2 and 5 years and show that patients gain life-years or have a lower mortality with pola-R-CHP. The green curve represents the optimistic scenario in which pola-R-CHP has a 75.1% 5-year PFS, and the blue curve represents the pessimistic scenario in which pola-R-CHP has a 5-year PFS of 62.6%.