Induced MYCNexpression in CD4+ T-cell mouse model shows interaction with EZH2 through a noncanonical function independent of PRC2. MYCN activation is sensitive to selective EZH2 degradation, which was synergistic with histone deacetylase inhibitors.
Induced MYCNexpression in CD4+ T-cell mouse model shows interaction with EZH2 through a noncanonical function independent of PRC2. MYCN activation is sensitive to selective EZH2 degradation, which was synergistic with histone deacetylase inhibitors.
