Relationship between somatic mutations and response to oral azacytidine and romidepsin. The chart compares and contrasts responders and nonresponders and epigenetic vs nonepigenetic genes. Each row represents a gene, and each column represents a patient. The number of separate colored boxes in a given gene/patient box denotes the number of mutations in that gene. ALK-ALCL, ALK-negative anaplastic large cell lymphoma; ATLL, adult T-cell leukemia/lymphoma; EATL, enteropathy-associated T-cell lymphoma; ENKTCL, extranodal natural killer (NK)/T-cell lymphoma; NOS, not otherwise specified.