Type 1 VWD patients with the same VWF gene variants have a comparable response to desmopressin. Each line represents a single patient. (A) Type 1 VWD patients with variants in exon 1 to 20. ¹Both patients also had R2313C. (B) Type 1 VWD patients with variants in exon 21 to 26. ²The patient with lower desmopressin response also had C1169W. (C) Type 1 VWD patients with variants in exon 27 to 29. ³Two patients also had 5170+10C>T. (D) Type 1 VWD patients with variants in exon 30 to 52.