DNMT3A mutations in peripheral T-cell lymphoma entities. (A) Heatmap of the molecular PTCL classification signatures. (B) Kaplan-Meier curve of the OS of PTCL cases included in this study. (C) Lollipop plot of DNMT3A mutations in PTCL-NOS molecular subtypes (top) and PTCLs of T_FH origin (bottom). Lollipops represent mutated residues; cases with >1 mutation plotted are identified numerically. Mutations in the dimerization region (S881-R887) past R882 (884, 885, 886, and 887) are stacked above for visual clarity. (D) Graph of the distribution of DNMT3A mutations per PTCL entity.