Frequency of cytogenetic risk groups and clinical responses for IgD myeloma. (Ai) Cytogenetic risk stratification of participants in the recent UK myeloma clinical trials (Myeloma IX and XI). Graph shows the percentage of the cytogenetic risk groups for the various myeloma subtypes. (Aii) Comparison proportions of the cytogenetic risk groups for IgD myeloma vs other myeloma subtypes. UHiR, ultra high risk; HiR, high risk; SR, standard risk; N/A, not available. (B) Clinical responses following induction therapy based on the IMWG response criteria. CR, complete response; VGPR, very good partial response; PR, partial response; SD; stable disease; PD, persistent disease; N/A, not available.