OS in patients aged <65 years with stage II to IV disease. (A-D) OS in patients with ALK⁺ ALCL (A) and in those with ALK⁻ ALCL, AITL, or PTCL NOS treated with CHOP or CHOEP in the first-line setting (C), with corresponding forest plots of HRs and 95% CIs (B,D), using multivariable Cox regression analysis.