Figure 3.
NLRP3 inflammasome inhibitors have varying effectiveness. WT and XIAP-deficient BMDMs were preincubated with various inhibitors as listed before stimulation with either CpG ODN or TNF-α. Levels of (A) secreted IL-1β and (B) TNF-α were measured. Symbols used: n.s for not significant, * for p≤0.05, and ** for p≤0.01.

NLRP3 inflammasome inhibitors have varying effectiveness. WT and XIAP-deficient BMDMs were preincubated with various inhibitors as listed before stimulation with either CpG ODN or TNF-α. Levels of (A) secreted IL-1β and (B) TNF-α were measured. Symbols used: n.s for not significant, * for p≤0.05, and ** for p≤0.01.

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