Expression of FcεRI subunit genes in hematopoietic progenitors is associated with a mast cell gene signature. (A) UMAP visualization of the single-cell transcriptomes of 6874 Lin⁻ c-Kit⁺ peripheral blood cells. The colors indicate Leiden clusters. Expression patterns of lineage genes used to annotate the landscape are provided in supplemental Figure 1. (B) Gene expression levels of mast cell genes and FcεRI subunit genes. (C) Gene expression of CD34. (D) Post-sort flow cytometry analysis of Lin⁻ c-Kit⁺ cells. The red contour plot shows back-gated FcεRI⁺ cells. One buffy coat was used to produce the data presented in this figure.