Figure 1.
Histogram comparing estimated glomerular filtration rates obtained by CKD-EPI–2009 and CKD-EPI–2021 equations in patients with sickle cell anemia. Green bars show eGFR using CKD-EPI–2009, while pink bars show eGFR using CKD-EPI–2021 (gray areas indicate overlap). The green and red curves are the density curves for the corresponding histograms. The mean (105.6 ± 35.4 mL/min per 1.73 m2 vs 106.4 ± 33.5 mL/min per 1.73 m2) and median (114.2 mL/min per 1.73 m2 [IQR, 82.5-132.1] vs 116.5 mL/min per 1.73 m2 [IQR, 85.9-131.6]) eGFR values obtained using CKD-EPI–2009, without adjustment for Black race, are very similar to those obtained using CKD-EPI–2021.

Histogram comparing estimated glomerular filtration rates obtained by CKD-EPI–2009 and CKD-EPI–2021 equations in patients with sickle cell anemia. Green bars show eGFR using CKD-EPI–2009, while pink bars show eGFR using CKD-EPI–2021 (gray areas indicate overlap). The green and red curves are the density curves for the corresponding histograms. The mean (105.6 ± 35.4 mL/min per 1.73 m2 vs 106.4 ± 33.5 mL/min per 1.73 m2) and median (114.2 mL/min per 1.73 m2 [IQR, 82.5-132.1] vs 116.5 mL/min per 1.73 m2 [IQR, 85.9-131.6]) eGFR values obtained using CKD-EPI–2009, without adjustment for Black race, are very similar to those obtained using CKD-EPI–2021.

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