LMP1 restores MYC-induced p-JNK expression, while LMP2A further increases p-JNK levels. Expression of MAPK family proteins in purified splenic B cells from (A) 4-week-old mice and (B) in tumor B cells. Representative immunoblots of MAPK family proteins are indicated. Phosphorylated JNK, phosphorylated ERK, and phosphorylated p38 expression were normalized to JNK, ERK, and p38, respectively. Dot plot graphs represent the mean ± standard deviation. P values were calculated by unpaired t test, *P < .05, **P < .01, ***P < .001, and ****P < .0001.