Tumor molecular differences by race and ethnicity. (A) Oncoplot of selected tumor somatic mutations in MM patients by race and ethnicity. Each row is a gene and vertical lines are individual patients, grouped by race and ethnicity. Each gene is counted once per patient, and colors represent the presence of different functional types of mutations. Selected mutations include the 5 most commonly mutated genes and those with racial and ethnic differences in prevalence at P ≤ 0.1. A comprehensive list of tumor somatic mutations in the MM genes (n = 35) and their frequencies by race and ethnicity is provided in supplemental Table 1. (B) Radar plot of the prevalence of selected tumor somatic mutations by race and ethnicity. (C) Racial and ethnic differences in RNA expression of MM genes that reached statistical significance at P < 0.05. Expression is normalized and displayed as log₂ (100× transcripts per million). P values for the pairwise comparisons are presented as *P < .05, **P < .01. ns, not statistically significant; SNV, single nucleotide variant.