Figure 1.
PHF6 associates with protein complexes involved in chromatin regulation and DNA repair. (A) Purified proteins after tandem affinity purification visualized by silver staining. Molecular weight marker is indicated on the left. (B) ConsensusPathDB over-representation analysis of protein complexes. (C) ConsensusPathDB over-representation analysis showing enrichment in chromatin remodeling pathways. (D) ConsensusPathDB over-representation analysis showing enrichment in DNA repair pathways. (E) ConsensusPathDB over-representation analysis showing enrichment in rRNA expression regulation pathways. ALL-1, leukemia acute lymphocytic susceptibility to 1; BAF, BRG1/BRM-associated factor; BRD7, bromodomain-containing protein 7; BRG1, brahma-related gene 1; CHD4, chromodomain helicase DNA binding protein 4; COMPASS, complex proteins associated with Set1; CoREST, RE1-silencing transcription factor corepressor; GG-NER, global-genome nucleotide excision repair; HCF1N, host cell factor 1; HDAC1/2, histone deacetylase 1/2; hSWI/SNF, human SWItch/sucrose nonfermentable; HuCHRAC, human chromatin accessibility complex; KIF1, kinesin family member 1a; LARC, LCR-associated remodeling complex; MBD3, methyl-CpG binding domain protein 3; MLL3/4, mixed-lineage leukemia-like protein 3/4; NuRD, nucleosome remodeling and deacetylase; PBAF, polybromo Brg1-associated factor; PRC2, polycomb repressive complex 2; RBBP4/7, retinoblastoma-binding protein 4/7; RMT, histone arginine methylase; RNA Pol I, RNA polymerase I; SETD1, SET domain containing 1A; SIN3, Swi-independent 3; SNF2h, sucrose nonfermenting 2 homolog; SNF5, switching defective/sucrose nonfermenting subunit 5.

PHF6 associates with protein complexes involved in chromatin regulation and DNA repair. (A) Purified proteins after tandem affinity purification visualized by silver staining. Molecular weight marker is indicated on the left. (B) ConsensusPathDB over-representation analysis of protein complexes. (C) ConsensusPathDB over-representation analysis showing enrichment in chromatin remodeling pathways. (D) ConsensusPathDB over-representation analysis showing enrichment in DNA repair pathways. (E) ConsensusPathDB over-representation analysis showing enrichment in rRNA expression regulation pathways. ALL-1, leukemia acute lymphocytic susceptibility to 1; BAF, BRG1/BRM-associated factor; BRD7, bromodomain-containing protein 7; BRG1, brahma-related gene 1; CHD4, chromodomain helicase DNA binding protein 4; COMPASS, complex proteins associated with Set1; CoREST, RE1-silencing transcription factor corepressor; GG-NER, global-genome nucleotide excision repair; HCF1N, host cell factor 1; HDAC1/2, histone deacetylase 1/2; hSWI/SNF, human SWItch/sucrose nonfermentable; HuCHRAC, human chromatin accessibility complex; KIF1, kinesin family member 1a; LARC, LCR-associated remodeling complex; MBD3, methyl-CpG binding domain protein 3; MLL3/4, mixed-lineage leukemia-like protein 3/4; NuRD, nucleosome remodeling and deacetylase; PBAF, polybromo Brg1-associated factor; PRC2, polycomb repressive complex 2; RBBP4/7, retinoblastoma-binding protein 4/7; RMT, histone arginine methylase; RNA Pol I, RNA polymerase I; SETD1, SET domain containing 1A; SIN3, Swi-independent 3; SNF2h, sucrose nonfermenting 2 homolog; SNF5, switching defective/sucrose nonfermenting subunit 5.

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