Robust in vivo xenograft model of patient-derived SS. (A) Schematic representation of the procedure used to generate the SS xenograft. (B-C) FC analysis of PB from mice at 8 weeks after transplantation with different numbers of SS cells from patient #23. (C) FC analysis with the indicated marker to confirm the outgrowth of malignant CD4⁺; CD7^– SS cells in the recipient mice. (D) Same analysis as in panel C from the bone marrow (BM) of a mouse transplanted with mononucleated cells from a healthy donor.