Figure 2.
Genomic and transcriptome of malignant plasma cells from primary PCL displaying t(11;14) compared with primary PCL without t(11;14). (A) Incidence of main cytogenetics abnormalities and mutations in 46 primary PCL displaying t(11;14) compared with 44 primary PCL without t(11;14), **P < .0001, *P < .01. (B) Kaplan-Meyer overall survival of primary PCL patients according to t(11;14). (C) Unsupervised clustering of 46 primary PCL displaying t(11;14) and 44 primary PCL without t(11;14) based on the expression levels of the 100 most variable genes. (D) Gene expression profiling comparing differentially expressed genes between primary PCL displaying t(11;14) and primary PCL without t(11;14), with at least twofold change (P < .05, FDR < .01). (E) GSEA from 46 primary PCL displaying t(11;14) and 44 primary PCL without t(11;14). FDR, false discovery rate.

Genomic and transcriptome of malignant plasma cells from primary PCL displaying t(11;14) compared with primary PCL without t(11;14). (A) Incidence of main cytogenetics abnormalities and mutations in 46 primary PCL displaying t(11;14) compared with 44 primary PCL without t(11;14), **P < .0001, *P < .01. (B) Kaplan-Meyer overall survival of primary PCL patients according to t(11;14). (C) Unsupervised clustering of 46 primary PCL displaying t(11;14) and 44 primary PCL without t(11;14) based on the expression levels of the 100 most variable genes. (D) Gene expression profiling comparing differentially expressed genes between primary PCL displaying t(11;14) and primary PCL without t(11;14), with at least twofold change (P < .05, FDR < .01). (E) GSEA from 46 primary PCL displaying t(11;14) and 44 primary PCL without t(11;14). FDR, false discovery rate.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal