Figure 1.
TAFAZZIN is dispensable for fetal liver myelopoiesis. (A) Flow cytometry gating strategy for fetal liver myeloid progenitor populations. Common myeloid progenitors (CMPs), megakaryocyte-erythrocyte progenitors (MEPs), and granulocyte-macrophage progenitors (GMPs) were identified based on CKIT, SCA1, CD16/32, and CD34 staining. (B) Myeloid progenitors were enumerated in the WT or TAFAZZIN-KO fetal livers harvested at embryonic days 14, 14.5, 15, 15.5, and 16. The numbers of fetal livers included in the analysis is indicated. (C) A focus on the frequency of GMPs, combined from the other panels, within the fetal livers of WT or TAFAZZIN-KO embryos shows as significant difference only at E14. Error bars indicate the mean ± SD. t tests were performed. *P < .05. Other results are not statistically significant.

TAFAZZIN is dispensable for fetal liver myelopoiesis. (A) Flow cytometry gating strategy for fetal liver myeloid progenitor populations. Common myeloid progenitors (CMPs), megakaryocyte-erythrocyte progenitors (MEPs), and granulocyte-macrophage progenitors (GMPs) were identified based on CKIT, SCA1, CD16/32, and CD34 staining. (B) Myeloid progenitors were enumerated in the WT or TAFAZZIN-KO fetal livers harvested at embryonic days 14, 14.5, 15, 15.5, and 16. The numbers of fetal livers included in the analysis is indicated. (C) A focus on the frequency of GMPs, combined from the other panels, within the fetal livers of WT or TAFAZZIN-KO embryos shows as significant difference only at E14. Error bars indicate the mean ± SD. t tests were performed. *P < .05. Other results are not statistically significant.

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