Representative magnetic resonance imaging of responders at baseline and initial time point of best overall response. (A) Patient 007 baseline scan demonstrating a 1.6 cm × 1.3 cm × 1.1 cm enhancing mass within the left posterior caudate body bordering the left lateral ventricle with complete resolution of enhancing lesion at month 4. Patient 008 baseline scan demonstrating a 1.4 cm × 1.4 cm × 0.5 cm enhancing mass in the left middle frontal gyrus corresponding to biopsy proven CNS lymphoma with complete resolution at month 3. (B) Patient 011 demonstrating leptomeningeal enhancement within the spinal cord and (C) CD19⁺ CD20⁺ CD5⁻ CD10⁻/dim leptomeningeal disease with monotypic κ immunoglobulin light chain expression at baseline, day +7 and month 1 demonstrating resolution following tisagenlecleucel infusion.