Disparity in hazard of leukemia death for NHB, Hispanic, and other race/ethnicity vs NHW patients, before and after controlling for specific domains that might mediate these disparities. Domains include structural racism (census tract measures), tumor biology (secondary leukemia and ELN prognostic score), health care access (insurance and clinical trial enrollment), treatment (induction therapy and transplant status), comorbidities, and ICU admission during treatment. HRs estimated from discrete-time survival models adjusting for sex, age, and study site. HRs and 95% CIs are presented separately by domain and race/ethnicity, before and after adjusting for each domain. Estimates are color coded before and after adjustment for each domain for NH Black (red and pink), Hispanic (dark blue and light blue), and other race/ethnicities (dark green and light green).