V and J (TRAV, TRAJ, TRGV, and TRGJ) usage in TCLs. The frequency of V and J segments of TCRα and TCRγ clonotypes are plotted as in Figure 7. The 2 most abundant TCRα^DNA and TCRγ^DNA clonotypes from TCLs and control samples were identified, and the frequency of V and J segments were plotted on the heat map. The RNA samples were used only for identification of the TCRα^RNA clonotypes. (A-B) TRAV and TRAJ segment usage; (C-D) TRGV and TRGJ segment usage.