One-way sensitivity analysis of the 10 most influential variables on the ICER. Figure 1 shows a tornado diagram of the 10 most influential model variables and their influence on the ICER. Variables were varied by 50% for costs and probabilities and by 10% for utilities as outlined in Table 1. Blue bars represent the lower value in the range, whereas red bars represent the higher value. Our model was most sensitive to the proportion of patients proceeding to allo-HCT. However, none of the variables included in our model was able to lower the ICER below the WTP threshold of $150 000/QALY gained.