Lesion response assessed by MRI. (A) KHE associated with KMP in a 2-month-old boy (patient 5618). He was treated with a combined therapy of sirolimus and prednisolone. (B) After 12 months of treatment, the reddish skin disappeared and evolved in size. (C) Coronal T2-weighted MRI changes in lesions before treatment. (D) A good lesion response was noted at month 12.