Treatment, treatment discontinuation, follow-up, and genetics. Swimmer’s plot of patients separated into 3 groups [del(17p) and TP53 mutated, unmutated TP53 and del(17p), and sole TP53 mutation]. Additionally, in green dots at the left, complex karyotypes (n = 4); in blue dots, highly complex karyotypes (n = 20) are marked. Red lines indicate patients under treatment, blue lines show patients in follow-up. Treatment discontinuation is indicated in 3 ways: black asterisks as regular discontinuation, red dots as irregular discontinuation, and 2 black lines as early discontinuation. Two deaths are indicated by crosses. Six progressions are indicated in red during follow-up (between cycles 24 and 34).