OS for all patients according to IDH1 and IDH2 mutations. Kaplan-Meier plots for OS of patients with AML with mutated IDH1: IDH1-R132C (blue), IDH1-R132H (green), IDH1 other (R132G, R132S, or R132L) (purple), and WT IDH (orange) (A) and mutated IDH2: IDH2-R140 (blue), IDH2-R172 (green), and WT IDH (orange) (B); time in months.