OS according to different mutational subtypes of IDH in ELN 2017 risk categories. Kaplan-Meier plots for OS of patients with AML according to ELN 2017 favorable-, intermediate-, and adverse-risk categories for patients with mutated IDH1 (blue), mutated IDH2 (green), and WT IDH1/2 (orange) (A) and for respective mutational variants of IDH1/2: IDH1-R132H (blue), IDH1-R132C (purple), IDH1 other (R132G, R132S, or R132L; yellow), IDH2-R140 (green), IDH2-R172 (turquoise), and WT IDH (orange) (B). P values were determined with the log-rank test; time in months.