OS of younger (age <60 years) patients. (A) OS in younger patients with NPM1^mut/PTPN11^wt (blue line) and NPM1^mut/PTPN11^mut (red line). (B) OS for younger patients based on the presence of NPM1^wt/PTPN11^wt (blue line) and NPM1^wt/PTPN11^mut (red line).