Model of HSC quiescence and self-renewal promoted by HBO1-mediated H3K14 acetylation (Ac). Deletion of Hbo1 results in downregulation of transcription factors (TFs) that are important for HSC maintenance, leading to increased differentiation. Professional illustration by Patrick Lane, ScEYEnce Studios.

Model of HSC quiescence and self-renewal promoted by HBO1-mediated H3K14 acetylation (Ac). Deletion of Hbo1 results in downregulation of transcription factors (TFs) that are important for HSC maintenance, leading to increased differentiation. Professional illustration by Patrick Lane, ScEYEnce Studios.

Close Modal

or Create an Account

Close Modal
Close Modal