Figure 3.
![Affinity constants of the dominant antibody affinity populations of FVIII-binding antibodies with confirmed FVIII specificity assessed for individual Ig isotypes and IgG subclasses. Presented are the apparent affinity constants of the dominant antibody affinity populations (KA [M−1]) of FVIII-binding antibodies with confirmed FVIII specificity, as described in the Materials and methods section. (A) Patients with nsHA. (B) Patients with sHA. (C) Healthy donors. KAs highlighted in red belong to patient 58 (nsHA).](https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/6/3/10.1182_bloodadvances.2021005745/5/advancesadv2021005745f3.png?Expires=1719038266&Signature=25K1W1E4W9RMt3zwm-8~3TmjZC-C3i1wHcq8eRgbalXkAsGVaYj2MiPnJa4GubOE6XNYyhv9FMdzTRxt1Wo8o598ujFN3d4WnsOBAg7XUhRGc6Q76ZsSEic9xC2JDacs5WnwRemNqSZhI8BkT1FUChvPPi~l~09Y8RVNFZHG151egJJTjoAShqRloKxWt4l1ZGiPaWwaEOu1GghPBqJ-8HBB6LMhQZtlBUiB-Lw4gR8t6Ac2joVbh3tAfHPVNuT6dwcj7zmJ88douIJ2tttciaFSSRDZF99LAJkfB0oXdV8bkDrddQH-ZRily9mdFdbcgbZUeE5aRA0yMowZBNx4jQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Affinity constants of the dominant antibody affinity populations of FVIII-binding antibodies with confirmed FVIII specificity assessed for individual Ig isotypes and IgG subclasses. Presented are the apparent affinity constants of the dominant antibody affinity populations (KA [M−1]) of FVIII-binding antibodies with confirmed FVIII specificity, as described in the Materials and methods section. (A) Patients with nsHA. (B) Patients with sHA. (C) Healthy donors. KAs highlighted in red belong to patient 58 (nsHA).