Figure 5.
Establishment of the LSC17 LDT in a second clinical diagnostic laboratory. (A) Plot showing correlation between LSC17 scores measured in 24 patient samples collected and processed at PM (red dots) and 36 patient samples collected and processed at Mayo Clinic (blue dots). Each sample was tested independently in the laboratories at both sites. The dotted line represents no difference between the paired score measurements. R, Spearman correlation coefficient. (B) Kaplan-Meier estimates of overall survival of 26 patients with AML from Mayo Clinic treated with intensive induction therapy, according to LSC17 score classified as high (above median) or low (below median) using the PM reference median score of 0.51.

Establishment of the LSC17 LDT in a second clinical diagnostic laboratory. (A) Plot showing correlation between LSC17 scores measured in 24 patient samples collected and processed at PM (red dots) and 36 patient samples collected and processed at Mayo Clinic (blue dots). Each sample was tested independently in the laboratories at both sites. The dotted line represents no difference between the paired score measurements. R, Spearman correlation coefficient. (B) Kaplan-Meier estimates of overall survival of 26 patients with AML from Mayo Clinic treated with intensive induction therapy, according to LSC17 score classified as high (above median) or low (below median) using the PM reference median score of 0.51.

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