NPM1 MRD distribution at relevant clinical time points according to DNMT3A^mut status. (A) NPM1 absolute transcript distribution in logarithmic scale. (B-G) MRD response, with MRD⁺ and MRD⁻ rates (B-D) and corresponding equivalent log10 reductions (E-G) at postinduction (B,E), post-C1 (C,F), and post-C2 (D,G).