Similar immune reconstitution patterns after posttransplant cyclophosphamide platforms. Immune reconstitution patterns for individual cell subsets over time are shown. The red lines represent transplantation from HLA-MSD, blue lines represent transplantation from HLA-MUD, and green lines represent transplantation from HLA-haplo with the interquartile range of normal donors shown in the gray bar. The P values (*P < .05, **P < .01, ***P < .001) are for a global (familywise) ANOVA test of differences in the immune reconstitution patterns between 3 different platforms after BMT. Nonsignificant P values were not shown. P values for testing differences in immune reconstitution after alloBMT between MSD and MUD were all >.05. P values shown in the plots were for testing differences between immune reconstitution after haplo and combined MSD/MUD alloBMT, only P values < .05 are shown. There were no statistically significant differences between MSD and MUD after BMT with PTCy. When comparing haplo with MSD/MUD alloBMT, differences were observed in CD3⁺ cells, Tconv, CD4⁺ T cells, CD8⁺ T cells, central memory (CM) CD8⁺ and effector memory (EM), and effector memory expressing RA (TEMRA) CD8⁺ cells. Differences in T cells were predominantly at day 28, where haplo alloBMT had lower absolute numbers, but these differences resolved over time for all subsets aside from CM CD8⁺ T cells that remained lower after haplo alloBMT even at 1 year. There were no significant post-BMT differences between haplo and MSD/MUD alloBMT immune recovery for absolute lymphocyte counts (ALC), B cells, natural killer (NK) cells, regulatory T cells, naïve CD4⁺ T cells, CM CD4⁺ T cells, TEMRA CD4⁺ T cells, or naïve CD8⁺ T cells. Number of individual samples analyzed per time point is highlighted in supplemental Table 2.