Figure 3.
Pooled analyses of ICH mortality for lifetime, children and young adults younger than 25 years, and neonates. The diamond represents the pooled estimate. (A) Pooled ICH mortality rates per 1000 person-years for lifetime cohorts. The study of Fransen van de Putte (2012)18 was excluded from the analysis because of overlap in the catchment area and population with the studies from Rosendaal et al (1989),44 Triemstra et al (1995),46 and Plug et al (2006).45 The study by Darby et al (2007)14 (HIV−) was excluded from the analysis because of overlap in the catchment area and population with the studies by Rizza and Spooner (1983)61 and Rizza et al (2001)62 (including HIV+ and HIV− patients). The results from the complete follow-up period (retrospective and prospective follow-up) from Zanon et al (2012)19 were used in this analysis because fatal events were not described for the prospective follow-up period only. (B) Pooled ICH mortality rates per 1000 person-years for children and young adults younger than 25 years. The studies by Andersson et al (2017),3 Traivaree et al (2007),23 Hu et al (2018),23 and Poonnoose et al (2017)69 did not include neonatal ICH. (C) Pooled ICH cumulative mortality per 100 live births for neonates.

Pooled analyses of ICH mortality for lifetime, children and young adults younger than 25 years, and neonates. The diamond represents the pooled estimate. (A) Pooled ICH mortality rates per 1000 person-years for lifetime cohorts. The study of Fransen van de Putte (2012)18 was excluded from the analysis because of overlap in the catchment area and population with the studies from Rosendaal et al (1989),44 Triemstra et al (1995),46 and Plug et al (2006).45 The study by Darby et al (2007)14 (HIV) was excluded from the analysis because of overlap in the catchment area and population with the studies by Rizza and Spooner (1983)61 and Rizza et al (2001)62 (including HIV+ and HIV patients). The results from the complete follow-up period (retrospective and prospective follow-up) from Zanon et al (2012)19 were used in this analysis because fatal events were not described for the prospective follow-up period only. (B) Pooled ICH mortality rates per 1000 person-years for children and young adults younger than 25 years. The studies by Andersson et al (2017),3 Traivaree et al (2007),23 Hu et al (2018),23 and Poonnoose et al (2017)69 did not include neonatal ICH. (C) Pooled ICH cumulative mortality per 100 live births for neonates.

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