A part of complex systems analysis done by Meier-Abt et al. The figure illustrates circular heatmap plot of the data derived from integrative proteomics and transcriptomics analyses of proteins and RNAs encoded by genes on chromosome 12 of CLL patients with or without trisomy 12. Coordinated, uncoordinated, and contradictory changes of these two elements are clearly demonstrated. See figure 3F in the article by Meier-Abt et al that appears on page 2514.