Figure 2.
Three-way Venn diagrams detailing the overlap between significantly dysregulated genes in patients with FA, SDS, and DC. Intersections between gene lists from DESeq2 analysis for each patient group in which FDR < 0.05. The Venn diagrams show the intersections between genes that are either all upregulated (A) or all downregulated (B). (C) String analysis of the 26 shared upregulated genes shows strong functional and physical association proteins encoded by the ribosome protein genes as well as those involved with mitochondrial function. Confidence in the interactions was set as high (>0.7) based on curated experimental data and co-expression studies. Only those genes with an interaction are shown.

Three-way Venn diagrams detailing the overlap between significantly dysregulated genes in patients with FA, SDS, and DC. Intersections between gene lists from DESeq2 analysis for each patient group in which FDR < 0.05. The Venn diagrams show the intersections between genes that are either all upregulated (A) or all downregulated (B). (C) String analysis of the 26 shared upregulated genes shows strong functional and physical association proteins encoded by the ribosome protein genes as well as those involved with mitochondrial function. Confidence in the interactions was set as high (>0.7) based on curated experimental data and co-expression studies. Only those genes with an interaction are shown.

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