Figure 2.
Kinetics of serum IgG, IgM, and IgA recovery in patients treated with anti-BCMA CAR T cells. (A) Box-and-whisker plots of IgG concentrations in patents with non-IgG MM at different time points before and after CAR T-cell infusion. (B) Cumulative incidence of IgG recovery. (C) Box-and-whisker plots of IgM concentrations in patients with non-IgM MM at different time points before and after CAR T-cell infusion. (D) Cumulative incidence of IgM recovery. (E) Box-and-whisker plots of IgA concentrations in patients with non-IgA MM at different time points before and after CAR T-cell infusion. (F) Cumulative incidence of IgA recovery. In panels A, C, and E, the median (bar) and interquartile range (box) are shown. The dotted line indicates the lower limit of normal. The significance of results are calculated by the Kruskal-Wallis test. *P < .05, **P < .01, ***P < .001, compared with baseline pretherapy levels.

Kinetics of serum IgG, IgM, and IgA recovery in patients treated with anti-BCMA CAR T cells. (A) Box-and-whisker plots of IgG concentrations in patents with non-IgG MM at different time points before and after CAR T-cell infusion. (B) Cumulative incidence of IgG recovery. (C) Box-and-whisker plots of IgM concentrations in patients with non-IgM MM at different time points before and after CAR T-cell infusion. (D) Cumulative incidence of IgM recovery. (E) Box-and-whisker plots of IgA concentrations in patients with non-IgA MM at different time points before and after CAR T-cell infusion. (F) Cumulative incidence of IgA recovery. In panels A, C, and E, the median (bar) and interquartile range (box) are shown. The dotted line indicates the lower limit of normal. The significance of results are calculated by the Kruskal-Wallis test. *P < .05, **P < .01, ***P < .001, compared with baseline pretherapy levels.

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