The recipient rs1260326 T allele is associated with an increased risk of stage 2 to 4 intestinal acute GVHD. (A) Cumulative incidence plots of stage 2 to 4 gut GVHD according to the recipient rs1260326 genotype in the combined discovery and replication cohorts. (B) Locus-zoom plot shows –log₁₀(P values) for association with stage 2 to 4 gut GVHD in the combined discovery and replication cohorts as a function of position in a 0.5 Mb region on either side of rs1260326 on chromosome 2 (chr2). Correlation coefficient r² values for linkage disequilibrium with rs1260326 are coded according to the inset. Genes within this region are displayed in the lower panel.