Figure 1.
Representative cerebral CT perfusion imaging of a patient. Representative imaging slices of the cerebral CT perfusion scans of a patient. Images include the localization images, cerebral blood flow slices, cerebral blood volume slices, minute transit time images, and PS product images at the time of remission and 6 months later. Of note, images of a normal brain would have minimal contrast leakage through the BBB (ie, minimal blue color). The red arrow indicates diffuse BBB leakage at month 0 (1.26 ml/min/100 g) with modest improvement at month 6 (0.96 ml/min/100 g), shown with yellow arrow. Please see supplemental Figure 1 for comparison of PS product images of diffuse BBB leakage in a patient with TTP, localized BBB leakage in a stroke patient, and minimal BBB leakage in another stroke patient.

Representative cerebral CT perfusion imaging of a patient. Representative imaging slices of the cerebral CT perfusion scans of a patient. Images include the localization images, cerebral blood flow slices, cerebral blood volume slices, minute transit time images, and PS product images at the time of remission and 6 months later. Of note, images of a normal brain would have minimal contrast leakage through the BBB (ie, minimal blue color). The red arrow indicates diffuse BBB leakage at month 0 (1.26 ml/min/100 g) with modest improvement at month 6 (0.96 ml/min/100 g), shown with yellow arrow. Please see supplemental Figure 1 for comparison of PS product images of diffuse BBB leakage in a patient with TTP, localized BBB leakage in a stroke patient, and minimal BBB leakage in another stroke patient.

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