Figure 5.
Profiles and enriched pathway analysis of decitabine-induced genes. (A) Venn diagram of overlapping genes of decitabine-altered genes in 4 responders. (B) Heat map of decitabine-altered genes in 4 responders with unsupervised clustering. Red to green colors represent relatively high to low gene expression, respectively, and gray indicates below the detectable level. (C) Venn diagram of overlapping genes of decitabine-altered genes in 3 nonresponders. (D) No overlap of decitabine-altered genes was observed between responders and nonresponders. (E-G) Pathways were predicted by Gene Ontology (E), KEGG (F), and Reactome (G) databases based on the expression changes of decitabine altered genes in 4 responders. AF, after; BE, before; NR, nonresponders; R, responders.

Profiles and enriched pathway analysis of decitabine-induced genes. (A) Venn diagram of overlapping genes of decitabine-altered genes in 4 responders. (B) Heat map of decitabine-altered genes in 4 responders with unsupervised clustering. Red to green colors represent relatively high to low gene expression, respectively, and gray indicates below the detectable level. (C) Venn diagram of overlapping genes of decitabine-altered genes in 3 nonresponders. (D) No overlap of decitabine-altered genes was observed between responders and nonresponders. (E-G) Pathways were predicted by Gene Ontology (E), KEGG (F), and Reactome (G) databases based on the expression changes of decitabine altered genes in 4 responders. AF, after; BE, before; NR, nonresponders; R, responders.

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