Three-year PFS and OS analysis for O-DLBCL and NO-DLBCL-GCB subentities. (A-B) Consistent with the prognostic importance of International Extranodal Lymphoma Study Group staging, PB-DLBCL and polyostotic-DLBCL displayed a significantly superior PFS and OS, compared with disseminated-DLBCL. (C-D) No significant difference in PFS or OS was shown for the subdivision of NO-DLBCL-GCB into extranodal, nodal, and mixed groups. (E-F) PB-DLBCL elucidated a significantly favorable PFS and OS, compared with equivalent Ann Arbor stage I/II NO-DLBCL-GCBs. (G-H) With respect to Ann Arbor stage III/IV, there was no difference in PFS or OS between disseminated-DLBCL and NO-DLBCL-GCB, although polyostotic-DLBCL showed improved survival.