Repopulating capacity of ALL subpopulations in vivo. (A) Cells from MRD low-risk patients 1-3 and 11 and risk patient 12 were sorted based on CD34/CD58, and (B) cells from low-risk patients 11 and 14 and risk patients 13, 15, and 22 were sorted based on CD34/CD97. Unsorted cells and sorted subfractions were evaluated for their ability to engraft primary and secondary NSG mouse recipients. Each patient is represented by a specific symbol, and each symbol depicts the engraftment as measured by human cells present in the BM of NSG mice. Pt., patient.