Figure 1.
Gene expression in unsorted cells and LPCs. (A) Gene expression of CD19, CD58, CD97, and CD200 in BM samples from 5 BCP-ALL patients (1, 12, 23, 61, 62) and from 5 healthy donors were analyzed using Agilent Whole Genome Oligo microarrays. Data show side-by-side comparisons of median centered normalized log2 signal intensities. (B) BCP-ALL patients were sorted on the basis of expression or lack of expression of CD34 and CD19. CD34+/CD38– HSCs were sorted from normal BM MNCs before gene expression analyses. Bars represent median normalized log2 intensities of expression, and error bars represent the interquartile ranges. Results were analyzed by 2-way analysis of variance (ANOVA) with Tukey’s post hoc testing. *P ≤ .05; **P ≤ .01; ***P ≤ .001.

Gene expression in unsorted cells and LPCs. (A) Gene expression of CD19, CD58, CD97, and CD200 in BM samples from 5 BCP-ALL patients (1, 12, 23, 61, 62) and from 5 healthy donors were analyzed using Agilent Whole Genome Oligo microarrays. Data show side-by-side comparisons of median centered normalized log2 signal intensities. (B) BCP-ALL patients were sorted on the basis of expression or lack of expression of CD34 and CD19. CD34+/CD38 HSCs were sorted from normal BM MNCs before gene expression analyses. Bars represent median normalized log2 intensities of expression, and error bars represent the interquartile ranges. Results were analyzed by 2-way analysis of variance (ANOVA) with Tukey’s post hoc testing. *P ≤ .05; **P ≤ .01; ***P ≤ .001.

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