Analysis of rearrangements detected by EuroClonality-NDC but not by EuroClonality/BIOMED-2 PCR. (A) ddPCR was performed using rearrangement-specific probes and primers on a subset of cases with available DNA. (B) Manual analysis of CNA data were performed to identify reduced coverage (<0.8-fold) of the intervening variable, diversity, and joining genes corresponding to the rearrangements identified by the ARResT/Interrogate pipeline. Each circle represents a sample with a rearrangement identified only by the EuroClonality-NDC assay. For both panels, blue shading indicates the rearrangement was detected by the respective technique, red shading signifies the rearrangement was not detected, and white shading indicates the sample was not tested. The y-axes represent the number of fragments identified by the ARResT/Interrogate pipeline corresponding to the specific clonal rearrangement.