Figure 3.
Expanded g-NK cells demonstrate robust persistence in vivo. Comparison of the number of human NK cells present in whole blood at days 6, 16, 26, and 31 postinjection (A), spleen at day 31 (B), and bone marrow (C) at day 31 between NSG mice infused with 1 × 107 g-NK or cNK cells (n = 3 for each arm) as measured by flow cytometry. To compare in vivo persistence between g-NK and cNK cells, a one-way ANOVA was performed with Bonferroni post hoc testing to determine differences between fresh or cryopreserved (Cryo) g-NK and cNK cells. Values are mean ± SEM. *P < .05; ***P < .001.

Expanded g-NK cells demonstrate robust persistence in vivo. Comparison of the number of human NK cells present in whole blood at days 6, 16, 26, and 31 postinjection (A), spleen at day 31 (B), and bone marrow (C) at day 31 between NSG mice infused with 1 × 107 g-NK or cNK cells (n = 3 for each arm) as measured by flow cytometry. To compare in vivo persistence between g-NK and cNK cells, a one-way ANOVA was performed with Bonferroni post hoc testing to determine differences between fresh or cryopreserved (Cryo) g-NK and cNK cells. Values are mean ± SEM. *P < .05; ***P < .001.

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