Figure 2.
Peak CAR T-cell expansion and associations with response, MRD, and toxicity. (A) Expansion and persistence of CAR T cells depicted as medians and IQRs. (B) Peak CAR T-cell levels by dose level, including in original vs revised AE management (1 × 106 cells per kg dose level). (C-F) Association between peak CAR T-cell expansion and ORR (C), MRD (D), grade ≥3 NEs (E), and grade ≥3 CRS (F). The horizontal line within each box represents the median, the lower and upper borders of each box represent the 25th and the 75th percentiles, respectively, and the error bars represent the 95% CI.

Peak CAR T-cell expansion and associations with response, MRD, and toxicity. (A) Expansion and persistence of CAR T cells depicted as medians and IQRs. (B) Peak CAR T-cell levels by dose level, including in original vs revised AE management (1 × 106 cells per kg dose level). (C-F) Association between peak CAR T-cell expansion and ORR (C), MRD (D), grade ≥3 NEs (E), and grade ≥3 CRS (F). The horizontal line within each box represents the median, the lower and upper borders of each box represent the 25th and the 75th percentiles, respectively, and the error bars represent the 95% CI.

Close Modal

or Create an Account

Close Modal
Close Modal