Figure 1.
Erythrocyte lysis with addition of the SARS-CoV-2 spike protein S1. Hemolysis is not increased with addition of the SARS-CoV-2 spike protein S1 to PNH erythrocytes. Addition of 40% aNHS with various concentrations of the spike protein to type O-positive erythrocytes from a patient with PNH (49% PNH red blood cell clone: 25% type III and 24% type II cells) and type O-positive erythrocytes from a healthy control, incubated at 37°C for 1 hour. Water (H2O) serves as a positive control. EDTA added to serum serves as an inhibitor of hemolysis. Data are shown as mean ± standard error of the mean of duplicate wells.