Risk benefit of SC to the pandemic influenza vaccine in anti-CD20–treated patients vs healthy controls. (A) On active therapy (<3 months from therapy). (B) Three to 6 months from therapy. (C) More than 12 months from therapy. Events, the number of patients with SC response to vaccination; Total, the total number of patients assessed for SC response to vaccination; Weight, the weighted contribution of each study to the meta-analysis.